ANTI-OBESITY INGREDIENTS

FUCOSTEROL
1.) Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes
2.) Fucosterol, isolated fromEcklonia stolonifera, inhibits adipogenesis through modulation of FoxO1 pathway in 3T3-L1 adipocytes
3.) Fucosterol inhibits adipogenesis through the activation of AMPK and Wnt/β-catenin signaling pathways
4.) Fucosterol inhibits adipogenesis through modulation of FoxO pathway in 3T3-L1 cells

FUCOXANTHIN
1.) Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin
2.) Nutraceutical Effects of Fucoxanthin for Obesity and Diabetes Therapy: A Review
3.) Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model
4.) Fucoxanthin in the management of obesity and its related disorders

GARDENIA JASMINOIDES
1.) Fruit of Gardenia jasminoides Induces Mitochondrial Activation and Non-Shivering Thermogenesis through Regulation of PPARγ
2.) Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in steroid induced insulin resistant rats
3.) GLP-1 secretagogues potential of medicinal plants in management of diabetes

GENISTEIN
1.) Genistein: A promising therapeutic agent for obesity and diabetes treatment
2.) Genistein inhibits high fat diet-induced obesity through miR-222 by targeting BTG2 and adipor1
3.) Genistein ameliorated obesity accompanied with adipose tissue browning and attenuation of hepatic lipogenesis in ovariectomized rats with high-fat diet

GYMNEMA SYLVESTRE
1.) A systematic review of Gymnema sylvestre in obesity and diabetes management
2.) Anti-obesity Effect of Gymnema sylvestre Extract on High Fat Diet-induced Obesity in Wistar Rats
3.) Effects of feeding a diet containing Gymnema sylvestre extract: Attenuating progression of obesity in C57BL/6J mice
4.) Evaluation of anti-obesity activity of Gymnema sylvestre leaves extract

HESPERIDIN
1.) Hesperidin: A Therapeutic Agent For Obesity
2.) Novel role of hesperidin improve obesity in HFD mice by modulating the composition of the gut microbiota
3.) Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation
4.) Anti-diabetic effect of hesperidin on palmitate (PA)-treated HepG2 cells and high fat diet-induced obese mice

MANGIFERIN
1.) Mangiferin Ameliorates Obesity-Associated Inflammation and Autophagy in High-Fat-Diet-Fed Mice: In Silico and In Vivo Approaches
2.) Mangifera indica leaves extract and mangiferin modulate CB1 and PPARγ receptors and others markers associated with obesity
3.) Evaluation of Antiobesity Effect of Mangiferin in Adipogenesis-Induced Human Mesenchymal Stem Cells by Assessing Adipogenic Genes

NARINGENIN
1.) Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21
2.) Could Naringenin Participate as a Regulator of Obesity and Satiety?
3.) Naringin Improves Diet-Induced Cardiovascular Dysfunction and Obesity in High Carbohydrate, High Fat Diet-Fed Rats
4.) Citrus flavonoid naringenin inhibits TLR2 expression in adipocytes

OLEOYLETHANOLAMIDE
1.) Oleoylethanolamide: A novel pharmaceutical agent in the management of obesity-an updated review
2.) A systematic review of the effects of oleoylethanolamide, a high-affinity endogenous ligand of PPAR-α, on the management and prevention of obesity
3.) Oleoylethanolamide: A fat ally in the fight against obesity
4.) Oleoylethanolamide, an endogenous PPAR-α agonist, lowers body weight and hyperlipidemia in obese rats

OLEUROPEIN
1.) Oleuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating β-adrenergic signaling
2.) Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings
3.) Biological activities of the natural antioxidant oleuropein: Exceeding the expectation – A mini-review

OROXYLUM INDICUM
1.) Oroxylum indicum (L.) Kurz extract inhibits adipogenesis and lipase activity in vitro
2.) Antiadipogenesis of Oroxylum indicum (L.) Kurz Extract via PPARγ2 in 3T3-L1 Adipocytes
3.) Oroxylin A, a constituent of Oroxylum indicum inhibits adipogenesis and induces apoptosis in 3T3-L1 cells
4.) Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

PAUSINYSTALIA JOHIMBE
1.) Yohimbine: The Effects on Body Composition and Exercise Performance in Soccer Players
2.) Effects of methanolic extract of Pausinystalia
yohimbe bark on blood glucose level in normal
fasting rats
3.) Cardiovascular effects of ephedrine, caffeine and yohimbine measured by thoracic electrical bioimpedance in obese women

PEGANUM HARMALA
1.) Peganum harmala enhanced GLP-1 and restored insulin signaling to alleviate AlCl3-induced Alzheimer-like pathology model
2.) GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration
3.) A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors

PHLORIZIN
1.) Phlorizin Supplementation Attenuates Obesity, Inflammation, and Hyperglycemia in Diet-Induced Obese Mice Fed a High-Fat Diet
2.) Phlorizin ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity
3.) Phlorizin treatment attenuates obesity and related disorders through improving BAT thermogenesis

PUERARIN
1.) Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling
2.) A Review of the Effects of Puerarin on Glucose and Lipid Metabolism in Metabolic Syndrome: Mechanisms and Opportunities
3.) Puerarin ameliorates hyperglycemia in HFD diabetic mice by promoting β-cell neogenesis via GLP-1R signaling activation

PYRROLOQUINOLINE (PQQ)
1.) Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression
2.) Pyrroloquinoline Quinone Attenuates Fat Accumulation in Obese Mice Fed with a High-Fat Diet, Daphnia magna Supplied with a High Amount of Food, and 3T3-L1 Adipocytes
3.) Mechanisms Behind Pyrroloquinoline Quinone Supplementation on Skeletal Muscle Mitochondrial Biogenesis: Possible Synergistic Effects with Exercise

R-ALA
1.) α-Lipoic Acid: A Multifunctional Antioxidant That Improves Insulin Sensitivity in Patients with Type 2 Diabetes
2.) Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy.
3.) alpha-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes.

RESVERATROL
1.) Resveratrol Increases Glucose Induced GLP-1 Secretion in Mice: A Mechanism which Contributes to the Glycemic Control
2.) Resveratrol: Anti-Obesity Mechanisms of Action
3.) The Role of Resveratrol Administration in Human Obesity
4.) Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?
